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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IREB2
All Species:
25.76
Human Site:
Y12
Identified Species:
40.48
UniProt:
P48200
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48200
NP_004127.1
963
105047
Y12
K
A
G
Y
A
F
E
Y
L
I
E
T
L
N
D
Chimpanzee
Pan troglodytes
XP_523125
963
104993
Y12
T
A
G
Y
A
F
E
Y
L
I
E
T
L
N
D
Rhesus Macaque
Macaca mulatta
XP_001107837
964
105069
Y12
K
A
G
Y
A
F
E
Y
L
I
E
T
L
N
D
Dog
Lupus familis
XP_532364
964
105327
Y12
G
A
G
R
P
F
E
Y
L
I
E
T
L
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q811J3
963
104918
Y12
S
A
G
Y
T
F
E
Y
L
I
E
T
L
N
G
Rat
Rattus norvegicus
Q62751
963
104783
Y12
S
A
G
Y
T
F
E
Y
L
I
E
T
L
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513243
1011
110449
Y58
I
T
G
C
P
F
E
Y
L
I
E
P
L
D
D
Chicken
Gallus gallus
Q5ZLQ4
965
105344
P12
R
P
G
S
P
Y
Q
P
I
I
E
E
L
R
N
Frog
Xenopus laevis
Q6NTP2
955
104418
T20
L
S
G
T
S
D
K
T
F
F
N
V
S
K
L
Zebra Danio
Brachydanio rerio
XP_001341791
896
98752
Y12
S
L
Q
N
E
H
P
Y
G
H
L
I
D
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
K12
N
P
F
A
Q
F
E
K
T
F
S
Q
A
G
T
Honey Bee
Apis mellifera
XP_392993
890
98796
S12
P
Y
N
H
L
M
K
S
I
K
I
G
L
K
E
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
I12
N
L
I
R
N
L
A
I
G
D
N
V
Y
K
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
A13
P
F
R
S
I
L
K
A
L
E
K
P
D
G
G
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
93.6
93.8
N.A.
84.4
82.1
68.5
62.9
N.A.
54.5
55.5
52.3
N.A.
Protein Similarity:
100
99.6
99.6
96.8
N.A.
96.6
97.1
N.A.
89.9
91.1
81
77
N.A.
72.4
71.8
67.5
N.A.
P-Site Identity:
100
93.3
100
80
N.A.
80
80
N.A.
60
26.6
6.6
6.6
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
93.3
100
80
N.A.
80
80
N.A.
66.6
60
26.6
6.6
N.A.
13.3
33.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.1
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.5
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
7
20
0
7
7
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
7
0
0
14
7
34
% D
% Glu:
0
0
0
0
7
0
54
0
0
7
54
7
0
0
7
% E
% Phe:
0
7
7
0
0
54
0
0
7
14
0
0
0
0
0
% F
% Gly:
7
0
60
0
0
0
0
0
14
0
0
7
0
14
20
% G
% His:
0
0
0
7
0
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
7
0
7
0
7
0
0
7
14
54
7
7
0
0
0
% I
% Lys:
14
0
0
0
0
0
20
7
0
7
7
0
0
20
0
% K
% Leu:
7
14
0
0
7
14
0
0
54
0
7
0
60
0
14
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
7
7
7
0
0
0
0
0
14
0
0
40
7
% N
% Pro:
14
14
0
0
20
0
7
7
0
0
0
14
0
0
0
% P
% Gln:
0
0
7
0
7
0
7
0
0
0
0
7
0
0
0
% Q
% Arg:
7
0
7
14
0
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
20
7
0
14
7
0
0
7
0
0
7
0
7
0
0
% S
% Thr:
7
7
0
7
14
0
0
7
7
0
0
40
0
7
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
34
0
7
0
54
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _